The role of the alpha1- and beta-adrenergic transduction pathways has been investigated in rainbow trout (Oncorhynchus mykiss) hepatic tissue. We have previously shown in American eel and bullhead hepatocytes that alpha1-adrenergic agonists are able to increase intracellular concentrations of IP3 and Ca2+ and to activate glycogenolysis. Our data suggest a marked variation in the liver of different fish both in terms of alpha1-binding sites affinity and of alpha1-adrenoceptor/IP3/Ca2+ transduction systems.
Characterization of adrenergic receptors and related transduction pathways in the liver of the rainbow trout.
CAPUZZO, Antonio;
1995
Abstract
The role of the alpha1- and beta-adrenergic transduction pathways has been investigated in rainbow trout (Oncorhynchus mykiss) hepatic tissue. We have previously shown in American eel and bullhead hepatocytes that alpha1-adrenergic agonists are able to increase intracellular concentrations of IP3 and Ca2+ and to activate glycogenolysis. Our data suggest a marked variation in the liver of different fish both in terms of alpha1-binding sites affinity and of alpha1-adrenoceptor/IP3/Ca2+ transduction systems.File in questo prodotto:
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