The title compound, 1-(2,3-dideoxy-2,3-difluoro-β-D-ribopentofuranosyl)thymine, C10H12F2N2O4, consists of an almost planar heterocyclic base moiety oriented anti with respect to a puckered sugar moiety. The sugar pucker is 2T3 and the N-glycosidic torsion angle is -119.6 (2)°. The conformation of the O5′ atom is +sc and the molecules are held together by a network of N-H-⋯O and O-H⋯O hydrogen bonds.
3'-deoxy-2',3'-difluorothymidine, a nucleoside analogue
BERTOLASI, Valerio;
1996
Abstract
The title compound, 1-(2,3-dideoxy-2,3-difluoro-β-D-ribopentofuranosyl)thymine, C10H12F2N2O4, consists of an almost planar heterocyclic base moiety oriented anti with respect to a puckered sugar moiety. The sugar pucker is 2T3 and the N-glycosidic torsion angle is -119.6 (2)°. The conformation of the O5′ atom is +sc and the molecules are held together by a network of N-H-⋯O and O-H⋯O hydrogen bonds.File in questo prodotto:
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