Enantiopure cis and trans -lactams 3a–e and 4a–e, respectively, have been synthesized via cycloaddition between chiral oxazolidinyl propynes 1a–b and nitrones 2a–d, in the presence of cuprous iodide (the Kinugasa reaction).
An asymmetric synthesis of beta-lactams: on the use of chiral oxazolidones in the Kinugasa reaction
BERTOLASI, Valerio
2002
Abstract
Enantiopure cis and trans -lactams 3a–e and 4a–e, respectively, have been synthesized via cycloaddition between chiral oxazolidinyl propynes 1a–b and nitrones 2a–d, in the presence of cuprous iodide (the Kinugasa reaction).File in questo prodotto:
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