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EnglishThe invention refers to a synthetic double-stranded oligonucleotide having a length comprised between 10 and 50 bases and a nucleic acid sequence selected from the group consisting of: (a) sequences corresponding to a selected portion of the promoter of human gamma-globin gene ; and (b) sequences corresponding to a selected portion of the human genomic region comprised between the gamma-globin gene and the delta-beta cluster, for use as an inducer of erythroid differentiation
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http://hdl.handle.net/11392/1188936| Titolo: | SYNTHETIC OLIGONUCLEOTIDES AS INDUCERS OF ERYTHROID DIFFERENTIATION |
| Autori interni: | BIANCHI, Nicoletta FERIOTTO, Giordana GAMBARI, Roberto MISCHIATI, Carlo |
| Data di pubblicazione: | 2001 |
| Abstract: | The invention refers to a synthetic double-stranded oligonucleotide having a length comprised between 10 and 50 bases and a nucleic acid sequence selected from the group consisting of: (a) sequences corresponding to a selected portion of the promoter of human gamma-globin gene ; and (b) sequences corresponding to a selected portion of the human genomic region comprised between the gamma-globin gene and the delta-beta cluster, for use as an inducer of erythroid differentiation |
| Handle: | http://hdl.handle.net/11392/1188936 |
| Appare nelle tipologie: | 06.1 Brevetto |
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