Objectives. To describe three cases of meningioma observed in a large cohort of 546 SLE patients followed at our Department in the last fifteen years. Methods. We identified three cases of meningioma among 181 SLE patients who underwent a brain MRI during their disease course (prevalence 1,65%). Results. All 3 SLE cases were women with a disease onset at 47, 18 and 42 years old respectively. All patients presented neuropsychiatric symptoms (NP) and had an incidental finding of a meningioma at brain MRI. One patient presented simultaneously a breast cancer. Only one patient had the surgical removal of the mass without improvement of her symptoms while in the other two the removal was not indicated. Conclusions. The association between meningioma and SLE may be a pure coincidence. However it draws our attention since its detection may represent a confounding factor in the setting of a NPSLE patient.
Meningioma and systemic lupus erythematosus: a matter of pure coincidence ?
CASTELLINO, Gabriella;BERNARDI, Simone;TROTTA, Francesco;GOVONI, Marcello
2009
Abstract
Objectives. To describe three cases of meningioma observed in a large cohort of 546 SLE patients followed at our Department in the last fifteen years. Methods. We identified three cases of meningioma among 181 SLE patients who underwent a brain MRI during their disease course (prevalence 1,65%). Results. All 3 SLE cases were women with a disease onset at 47, 18 and 42 years old respectively. All patients presented neuropsychiatric symptoms (NP) and had an incidental finding of a meningioma at brain MRI. One patient presented simultaneously a breast cancer. Only one patient had the surgical removal of the mass without improvement of her symptoms while in the other two the removal was not indicated. Conclusions. The association between meningioma and SLE may be a pure coincidence. However it draws our attention since its detection may represent a confounding factor in the setting of a NPSLE patient.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
