The antidiuretic drug desmopressin acetate (DDAVP) is a cyclic peptide drug commonly administered via the nose, given its very poor oral bioavailability. Here, we studied a preservative-free immediate release powder formulation for nasal administration of desmopressin as an alternative to conventional liquid nasal formulations.

In vitro and in vivo study of a desmopressin nasal powder

COLOMBO, Gaia;DALPIAZ, Alessandro;FERRARO, Luca Nicola;BORTOLOTTI, Fabrizio
2007

Abstract

The antidiuretic drug desmopressin acetate (DDAVP) is a cyclic peptide drug commonly administered via the nose, given its very poor oral bioavailability. Here, we studied a preservative-free immediate release powder formulation for nasal administration of desmopressin as an alternative to conventional liquid nasal formulations.
2007
9781933722078
Desmopressin; preservatives; nasal powder; chimera agglomerates
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/534033
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