With tha aim to investigatethe effect of hydrophylic environments at the C-terminal position, we synthesised in solution several Phe-D-Leu-Phe-D-Leu-Y derivatives (y=Lys, glu, tyr) in which different ureido substituents were included at their N-terminal. The biological action was analysed on human neutrophils
N-ureido peptide derivatives as antagonists towar human neutrophil formylpeptide receptor
DALPIAZ, Alessandro;SPISANI, Susanna;FERRETTI, Maria Enrica;TRANIELLO, Maria Serena;VERTUANI, Gianni
2000
Abstract
With tha aim to investigatethe effect of hydrophylic environments at the C-terminal position, we synthesised in solution several Phe-D-Leu-Phe-D-Leu-Y derivatives (y=Lys, glu, tyr) in which different ureido substituents were included at their N-terminal. The biological action was analysed on human neutrophilsFile in questo prodotto:
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