The effect of solid lipid microparticles on the photostability and human stratum corneum penetration of the sunscreen agent 4-methylbenzylidene camphor was studied. The light-induced decompossition of 4-methylbenzylidene camphor in the emulsion vehicle wa significantly reduced by encapsulation into the lipoparticles. Moreover, the in vivo penetration studies demonstrated tha the permeation of 4-methylbenzylidene camphor to the deeper regions of the horny layer was markedly decreased upon application of the microencapsulated sunscreen agent.
Encapsulation of the sunscreen agent, 4-methylbenzylidene camphor in lipid microparticles:effect on photostability and percutaneous penetration
SCALIA, Santo;
2007
Abstract
The effect of solid lipid microparticles on the photostability and human stratum corneum penetration of the sunscreen agent 4-methylbenzylidene camphor was studied. The light-induced decompossition of 4-methylbenzylidene camphor in the emulsion vehicle wa significantly reduced by encapsulation into the lipoparticles. Moreover, the in vivo penetration studies demonstrated tha the permeation of 4-methylbenzylidene camphor to the deeper regions of the horny layer was markedly decreased upon application of the microencapsulated sunscreen agent.File in questo prodotto:
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