The incubation of rabbit heart mitochondria in the presence of ferrous ions induced lipid peroxidation which was accompanied by a reduction of mitochondrial respiratory capacity and Ca++ transport. The effects were more evident, when pyruvate was employed as respiratory substrate, and were partially prevented by catalase, while superoxide dismutase was ineffective.
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Data di pubblicazione: | 1988 | |
Titolo: | Effect of lipid peroxidation on heart mitochondria oxygen consuming and calcium transporting capacities. | |
Autori: | C. Ceconi; S. Curello; A. Albertini; R. Ferrari | |
Rivista: | MOLECULAR AND CELLULAR BIOCHEMISTRY | |
Abstract: | The incubation of rabbit heart mitochondria in the presence of ferrous ions induced lipid peroxidation which was accompanied by a reduction of mitochondrial respiratory capacity and Ca++ transport. The effects were more evident, when pyruvate was employed as respiratory substrate, and were partially prevented by catalase, while superoxide dismutase was ineffective. | |
Handle: | http://hdl.handle.net/11392/524567 | |
Appare nelle tipologie: | 03.1 Articolo su rivista |
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