The incubation of rabbit heart mitochondria in the presence of ferrous ions induced lipid peroxidation which was accompanied by a reduction of mitochondrial respiratory capacity and Ca++ transport. The effects were more evident, when pyruvate was employed as respiratory substrate, and were partially prevented by catalase, while superoxide dismutase was ineffective.
Effect of lipid peroxidation on heart mitochondria oxygen consuming and calcium transporting capacities.
CECONI, Claudio;FERRARI, Roberto
1988
Abstract
The incubation of rabbit heart mitochondria in the presence of ferrous ions induced lipid peroxidation which was accompanied by a reduction of mitochondrial respiratory capacity and Ca++ transport. The effects were more evident, when pyruvate was employed as respiratory substrate, and were partially prevented by catalase, while superoxide dismutase was ineffective.File in questo prodotto:
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