SV40, BKV and JCV sequences were investigated by PCR DNA amplification followed by filter hybridization in a series of human brain lymphomas obtained from human immunodeficiency virus (HIV)-seronegative and HIV-infected patients. Our PCR and filter hybridization conditions were set up to detect specifically the SV40, BKV and JCV sequences. None of the samples under investigation were found positive for the polyomavirus footprints. These results suggest that the brain lymphomas are not associated with the DNA tumor polyomavirus.
No association between polyomaviruses and primary central nervous system lymphomas of HIV-seronegative and HIV-positive patients
MARTINI, Fernanda;TOGNON, Mauro
2004
Abstract
SV40, BKV and JCV sequences were investigated by PCR DNA amplification followed by filter hybridization in a series of human brain lymphomas obtained from human immunodeficiency virus (HIV)-seronegative and HIV-infected patients. Our PCR and filter hybridization conditions were set up to detect specifically the SV40, BKV and JCV sequences. None of the samples under investigation were found positive for the polyomavirus footprints. These results suggest that the brain lymphomas are not associated with the DNA tumor polyomavirus.File in questo prodotto:
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