The gating of an artificial receptor was monitored for the first time by impedance spectroscopy in tethered lipid bilayers. Subnanomolar concentrations of antibody were detected by modulation of the channel activity. The principle of gating by an antibody is particularly attractive because of its general character, and thus opens new possibilities for immunosensing.
Immunosensing by a synthetic ligand-gated ion channel
GUERRINI, Remo;
2001
Abstract
The gating of an artificial receptor was monitored for the first time by impedance spectroscopy in tethered lipid bilayers. Subnanomolar concentrations of antibody were detected by modulation of the channel activity. The principle of gating by an antibody is particularly attractive because of its general character, and thus opens new possibilities for immunosensing.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
