The title compound crystallizes in the orthorhombic space group P212121 with a=5.084(1), b=14.322(3), c=16.065(2)Å, Z=4. The structure was solved by the heavy atom method and refined by full-matrix least-squares calculations to a final R value of 0.033 for 1106 unique observed reflections. The N-glycosidic torsion angle x has a value of -153.7(4)°, in the anti-range. The sugar pucker is2T3 with P=175(1)° and ψ=30(1)°. The C4′-C5′ conformation is + sc with γ=46.7(7)°. The structure is stabilized by N-H⋯N, N-H⋯O and O-H⋯O hydrogen bonds and C-H⋯O close contacts. © 1993 Plenum Publishing Corporation.
Crystal structure of a nucleoside analog: 2′,3′-dideoxy-3′-fluoro-5-bromocytidine
BERTOLASI, Valerio;
1993
Abstract
The title compound crystallizes in the orthorhombic space group P212121 with a=5.084(1), b=14.322(3), c=16.065(2)Å, Z=4. The structure was solved by the heavy atom method and refined by full-matrix least-squares calculations to a final R value of 0.033 for 1106 unique observed reflections. The N-glycosidic torsion angle x has a value of -153.7(4)°, in the anti-range. The sugar pucker is2T3 with P=175(1)° and ψ=30(1)°. The C4′-C5′ conformation is + sc with γ=46.7(7)°. The structure is stabilized by N-H⋯N, N-H⋯O and O-H⋯O hydrogen bonds and C-H⋯O close contacts. © 1993 Plenum Publishing Corporation.File in questo prodotto:
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