A series of 3-(benzimidazol-2-yl)propionic acids substituted at the N1 nitrogen with Me and benzyl groups and at the C5 and C6 positions with chloro, methoxy, amino, hydroxyl groups were synthesized and tested as TXA2 receptor antagonists. None of the compds. showed any antiaggregating activity.
Design and synthesis of 3-(benzimidazol-2-yl)propionic acids as thromboxane A2 receptor antagonists
BARALDI, Pier Giovanni;
1993
Abstract
A series of 3-(benzimidazol-2-yl)propionic acids substituted at the N1 nitrogen with Me and benzyl groups and at the C5 and C6 positions with chloro, methoxy, amino, hydroxyl groups were synthesized and tested as TXA2 receptor antagonists. None of the compds. showed any antiaggregating activity.File in questo prodotto:
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