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EnglishExacerbations in chronic obstructive pulmonary disease (COPD) are major contributors to worsening lung function, impaired quality of life, emergency healthcare use and COPD-related mortality. COPD exacerbations are heterogeneous in terms of airway inflammation and aetiology. About 60% of COPD patients have blood eosinophil counts of ≥2%, which appears to be associated with an increased risk of exacerbations [1–3]. However, the association between blood eosinophil counts at stable disease and COPD exacerbations in the subsequent year is incompletely understood.
| Data di pubblicazione: | 2017 | |
| Titolo: | Blood eosinophil count and exacerbation risk in patients with COPD | |
| Autori: | Kerkhof, Marjan; Sonnappa, Samatha; Postma, Dirkje S.; Brusselle, Guy; Agustã, Alvar; Anzueto, Antonio; Jones, Rupert; Papi, Alberto; Pavord, Ian; Pizzichini, Emilio; Popov, Todor; Roche, Nicolas; Ryan, Dermot; Thomas, Mike; Vogelmeier, Claus; Chisholm, Alison; Freeman, Daryl; Bafadhel, Mona; Hillyer, Elizabeth V.; Price, David B. | |
| Rivista: | EUROPEAN RESPIRATORY JOURNAL | |
| Keywords: | Eosinophils; COPD exacerbation | |
| Abstract in inglese: | Exacerbations in chronic obstructive pulmonary disease (COPD) are major contributors to worsening lung function, impaired quality of life, emergency healthcare use and COPD-related mortality. COPD exacerbations are heterogeneous in terms of airway inflammation and aetiology. About 60% of COPD patients have blood eosinophil counts of ≥2%, which appears to be associated with an increased risk of exacerbations [1–3]. However, the association between blood eosinophil counts at stable disease and COPD exacerbations in the subsequent year is incompletely understood. | |
| Digital Object Identifier (DOI): | 10.1183/13993003.00761-2017 | |
| Handle: | http://hdl.handle.net/11392/2375577 | |
| Appare nelle tipologie: | 03.1 Articolo su rivista |
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|---|---|---|---|---|
| 1700761.full.pdf | Full text editoriale | Full text (versione editoriale) | PUBBLICO - Pubblico con Copyright | Open Access Visualizza/Apri |
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