Dermoscopy of isolated syringoma of the vulva

Syringoma is a benign adnexal tumor deriving from intraepidermal eccrine ducts that occurs predominantly in young women.1 Syringomas appear as small, firm, skin-colored or slightly yellow, asymptomatic or less frequently pruritic, soft papules, often in multiples with bilateral and symmetric distribution. They typically involve the periorbital region whereas vulvar involvement has been rarely reported. Diagnosis of vulvar syringoma may be overlooked when papules are asymptomatic or solitary and no other lesions are present elsewhere. Vulvar syringoma should be in the differential diagnosis of many other papular lesions, such as Fox-Fordyce disease, epidermal cysts, milias, senile angiomas, condyloma acuminata, steatocystoma multiplex, lymphangioma circumscriptum, and lichen simplex chronicus. Although the diagnosis of vulvar syringoma could be made only by histopathological examination, dermoscopy may contribute toward identification of this tumor, especially by revealing its characteristic multiple bright yellowish cystic enlargements.