The N, N′-dimethylformamide solvated crystal of the drug nitrofurantoin has been prepared and analysed by single-crystal X-ray diffraction. The two co-crystallized molecules, in the 1 : 1 stoichiometric ratio, are linked by a medium/strong N–H···O hydrogen bond (N···O is 2.759 (3) Å) and a weaker C–H···O interaction to form isolated supramolecular adducts, that in turn are packed into the lattice framework mainly through C–H···O hydrogen bonds. Two-dimensional fingerprint plots of Hirshfeld surfaces are used to visualize, analyze and compare intermolecular interactions found in the title compound and in similar structures.
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Data di pubblicazione: | 2016 | |
Titolo: | Crystal structure and packing analysis of nitrofurantoin N,N-dimethylformamide solvate | |
Autori: | Cvetkovski, A; Ferretti, V. | |
Rivista: | CRYSTALLOGRAPHY REPORTS | |
Parole Chiave: | Chemistry (all); Materials Science (all); Condensed Matter Physics | |
Abstract in inglese: | The N, N′-dimethylformamide solvated crystal of the drug nitrofurantoin has been prepared and analysed by single-crystal X-ray diffraction. The two co-crystallized molecules, in the 1 : 1 stoichiometric ratio, are linked by a medium/strong N–H···O hydrogen bond (N···O is 2.759 (3) Å) and a weaker C–H···O interaction to form isolated supramolecular adducts, that in turn are packed into the lattice framework mainly through C–H···O hydrogen bonds. Two-dimensional fingerprint plots of Hirshfeld surfaces are used to visualize, analyze and compare intermolecular interactions found in the title compound and in similar structures. | |
Digital Object Identifier (DOI): | 10.1134/S1063774516040040 | |
Handle: | http://hdl.handle.net/11392/2353967 | |
Appare nelle tipologie: | 03.1 Articolo su rivista |