The present invention relates to muteins of hNGF, their therapeutic uses and pharmaceutical compositions. In particular, the muteins o f the invention are selectively recognised by a specific reagent with regard to endogenous hNGF. The muteins are obtained by at least one amino acid substitution residing in loop III of hNGF.
Muteins of hNGF, therapeutic uses and pharmaceutical compositions
CAPSONI, Simona;
2006
Abstract
The present invention relates to muteins of hNGF, their therapeutic uses and pharmaceutical compositions. In particular, the muteins o f the invention are selectively recognised by a specific reagent with regard to endogenous hNGF. The muteins are obtained by at least one amino acid substitution residing in loop III of hNGF.File in questo prodotto:
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