Among the small-sized organic components of natural waters, the so-called humic monomers (building blocks of humic substances) can affect the efficiency of wastewater treatment plants (WWTPs) based on adsorption processes, due to their dimension comparable to those of the sorbent pores. Recently, the environmental antibiotic spreading is of concern because of the antibiotic-resistance development. Several studies report about the occurrence in surface waters and WWTPs/hospital effluents of sulfonamides, a top-selling class of antibiotics systematically used as growth promoters and to treat/prevent bacterial infections, owing to their anionic nature. Adsorption on high silica (HS) zeolites has been proposed as an efficient technique to remove high amount of sulfonamides with a favourable kinetics in model studies but no information is available about the effect of humic monomers on their efficiency [Ref]. Here the adsorption/desorption of sulfamethoxazole (SMX) sulfonamide on a HS zeolite Y was investigated in the presence of two humic monomers: vanillin (VNL) and caffeic acid (CA). VNL competed with SMX for the zeolite adsorption sites, conversely to what observed for CA, according to their solubility and pKa values. As SMX-VNL co-adsorption was revealed, FTIR spectroscopy combined to Rietveld analysis of XRPD data allowed to define the guest-guest interactions inside the zeolite pores. DFT calculations in vacuo confirmed the stabilization of the complex (see figure) with respect to the isolated compounds. Finally, both thermal treatment and solvent extraction succeeded in the regeneration of the exhausted zeolite. [Ref] Leardini et al., Martucci et al., 2014 Min. Mag.; Blasioli et al., 2014 J. Coll .Interface Sci.; Braschi et al., 2013 RSC-Advances; Martucci et al. 2013 Micropor. Mesopor. Mat.; Braschi et al., 2010 Langmuir; Braschi et al., 2010 J. Hazard. Mat. Research co-funded by the Italian Ministry of Education, University, and Research (2008 BL2NWK)

Adsorption selectivity of veterinary sulfonamide antibiotics and humic monomers by zeolite Y and regeneration studies: A zeolite-based WWTP technology against antibiotic resistance

MARTUCCI, Annalisa
2015

Abstract

Among the small-sized organic components of natural waters, the so-called humic monomers (building blocks of humic substances) can affect the efficiency of wastewater treatment plants (WWTPs) based on adsorption processes, due to their dimension comparable to those of the sorbent pores. Recently, the environmental antibiotic spreading is of concern because of the antibiotic-resistance development. Several studies report about the occurrence in surface waters and WWTPs/hospital effluents of sulfonamides, a top-selling class of antibiotics systematically used as growth promoters and to treat/prevent bacterial infections, owing to their anionic nature. Adsorption on high silica (HS) zeolites has been proposed as an efficient technique to remove high amount of sulfonamides with a favourable kinetics in model studies but no information is available about the effect of humic monomers on their efficiency [Ref]. Here the adsorption/desorption of sulfamethoxazole (SMX) sulfonamide on a HS zeolite Y was investigated in the presence of two humic monomers: vanillin (VNL) and caffeic acid (CA). VNL competed with SMX for the zeolite adsorption sites, conversely to what observed for CA, according to their solubility and pKa values. As SMX-VNL co-adsorption was revealed, FTIR spectroscopy combined to Rietveld analysis of XRPD data allowed to define the guest-guest interactions inside the zeolite pores. DFT calculations in vacuo confirmed the stabilization of the complex (see figure) with respect to the isolated compounds. Finally, both thermal treatment and solvent extraction succeeded in the regeneration of the exhausted zeolite. [Ref] Leardini et al., Martucci et al., 2014 Min. Mag.; Blasioli et al., 2014 J. Coll .Interface Sci.; Braschi et al., 2013 RSC-Advances; Martucci et al. 2013 Micropor. Mesopor. Mat.; Braschi et al., 2010 Langmuir; Braschi et al., 2010 J. Hazard. Mat. Research co-funded by the Italian Ministry of Education, University, and Research (2008 BL2NWK)
2015
sulfonamide antibiotics, humic monomers, zeolite Y, regeneration
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2340929
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact