In this issue of the Biochemical Journal, Wu et al. describe the characterization of new low-affinity Ca2 + indicators for monitoring Ca2 + levels in both the ER (endoplasmic reticulum) and mitochondria. In contrast with other ER Ca2 + sensors, these indicators emit in the red part of the spectrum, allowing for their use in combination with GFP-based probes and expanding the genetically encoded tool kit for the measurement of Ca2 + inside organelles.
The RED light is on! New tools for monitoring Ca2+ dynamics in the endoplasmic reticulum and mitochondria
MARCHI, Saverio;PINTON, Paolo
2014
Abstract
In this issue of the Biochemical Journal, Wu et al. describe the characterization of new low-affinity Ca2 + indicators for monitoring Ca2 + levels in both the ER (endoplasmic reticulum) and mitochondria. In contrast with other ER Ca2 + sensors, these indicators emit in the red part of the spectrum, allowing for their use in combination with GFP-based probes and expanding the genetically encoded tool kit for the measurement of Ca2 + inside organelles.File in questo prodotto:
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