03 Contributo in rivista (Pubblicazione in Rivista)

03 Contributo in rivista (Pubblicazione in Rivista): [57002] Home page macrotipologia

Sfoglia

Prodotti recenti

Outcomes of Locally Advanced Rectal Cancer Patients Treated with Total Neoadjuvant Treatment: A Meta-Anaysis of Randomized Controlled Trials

Determining outcomes using the total neoadjuvant therapy (TNT) in patients with local advanced rectal cancer is important for stratifying patients according to expected outcomes in future studies in the era of treatment combination. The present meta-analysis estimated the pathological complete response, disease-free survival, and overall survival probabilities of rectal cancer patients and identified predictors of outcomes.

On negative effective mass and negative group velocity in anharmonic seismic metamaterials

In this work, an anharmonic mass-in-mass system that can be employed as a nonlinear seismic metamaterial is represented as an equivalent anharmonic mass-spring system via an effective medium approach. The dispersion relation and the behavior of the effective mass as a function of the angular frequency obtained in the regime of weak anharmonicity deviate from those of the corresponding linear system because of the effect of the fourth-order potential anharmonicity. In the presence of anharmon...

From Thermodynamics to Information: Landauer’s Limit and Negentropy Principle Applied to Magnetic Skyrmions

Magnetic skyrmions are topological swirling spin textures objects that can be manipulated and employed as information carriers. This is accomplished based either on their ground-state properties or their thermodynamic properties. Landauer’s principle establishes an irreversible conversion from information to physics. The inverse mechanism, the inverse mechanism is proposed for magnetic topological defects forming in magnetic nanostructures that are regarded as closed thermodynamic systems con...

Preclinical effects of cannabidiol in an experimental model of migraine

Migraine is a disabling disorder characterized by recurrent headaches, accompanied by abnormal sensory sensitivity and anxiety. Despite extensive historical use of cannabis in headache disorders, there is limited research on the nonpsychoactive cannabidiol (CBD) for migraine and there is no scientific evidence to prove that CBD is an effective treatment. The effects of CBD are examined here using a calcitonin gene-related peptide (CGRP)-induced migraine model that provides measures of cephali...

Conjugation, Prodrug, and Co-Administration Strategies in Support of Nanotechnologies to Improve the Therapeutic Efficacy of Phytochemicals in the Central Nervous System

Phytochemicals, produced as secondary plant metabolites, have shown interesting potential therapeutic activities against neurodegenerative diseases and cancer. Unfortunately, poor bioavailability and rapid metabolic processes compromise their therapeutic use, and several strategies are currently proposed for overcoming these issues. The present review summarises strategies for enhancing the central nervous system's phytochemical efficacy. Particular attention has been paid to the use of phyto...

Scopri

Accesso al fulltext

no fulltext40461
open8154
reserved5342
partially open3038
mixed4
embargoed2
restricted1

SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara