Mesalazine (5-ASA) is an anti-inflammatory drug used for ulcerative colitis or Crohn’s disease. Most of available oral 5-ASA dosage forms are modified release tablets targeting the colon. However, in paediatrics patient compliance would improve by avoiding dosage forms that cannot be swallowed by children. The aim of this work was to develop gastro-resistant multiparticulate dosage forms for mesalazine colon delivery with easier dose intake by children.
A Study for the Development of Mesalazine Multiparticulate Dosage Forms for Colon Delivery in Pediatric Patients
COLOMBO, Gaia
2008
Abstract
Mesalazine (5-ASA) is an anti-inflammatory drug used for ulcerative colitis or Crohn’s disease. Most of available oral 5-ASA dosage forms are modified release tablets targeting the colon. However, in paediatrics patient compliance would improve by avoiding dosage forms that cannot be swallowed by children. The aim of this work was to develop gastro-resistant multiparticulate dosage forms for mesalazine colon delivery with easier dose intake by children.File in questo prodotto:
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