This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfuidic approach. The effect of different production parameters has been investigated for their effect on PM-MTH characteristics.

Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia

MAZZITELLI, Stefania;BROGNARA, Eleonora;LAMPRONTI, Ilaria;GAMBARI, Roberto;NASTRUZZI, Claudio
2012

Abstract

This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfuidic approach. The effect of different production parameters has been investigated for their effect on PM-MTH characteristics.
2012
Capretto, L.; Mazzitelli, Stefania; Brognara, Eleonora; Lampronti, Ilaria; Carugo, D.; Hill, M.; Zhang, X.; Gambari, Roberto; Nastruzzi, Claudio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1681418
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