Patients with polycystic ovaries and at risk of a very high response to human urinary gonadotrophin administration were stimulated with a low dose step-up protocol, using highly purified urinary FSH. This protocol did not lead to exagerated ovarian response and no hyperstimulation syndrome was observed in the 52 treated patients. Oocytes were of good quality and fertilized normally (>50%). After transfer of fresh and frozen-thawed embryos, 32 patients (61.5%) became pregnant and 29 (55.7%) delivered.
Succesfull low dose step up stimulation protocol in patients with policystic ovaries at risk of a very high ovarian response to gonadotrophine. Infertility and assisted reproductive tecnology. From Research to therapy.
MARCI, Roberto;
1997
Abstract
Patients with polycystic ovaries and at risk of a very high response to human urinary gonadotrophin administration were stimulated with a low dose step-up protocol, using highly purified urinary FSH. This protocol did not lead to exagerated ovarian response and no hyperstimulation syndrome was observed in the 52 treated patients. Oocytes were of good quality and fertilized normally (>50%). After transfer of fresh and frozen-thawed embryos, 32 patients (61.5%) became pregnant and 29 (55.7%) delivered.File in questo prodotto:
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