Steroid compounds can be ranked among the most widely marketed products from the pharmaceutical industry.1 Highly specific reactions are required to produce functionalized compounds with therapeutic use and commercial value. The complexity of steroid molecules renders the use of biocatalysts particularly interesting, due to the high regio- and stereo-selectivity of the reactions to be performed. In the field the biotrasformations of cortisone (17α,21-dihydroxy-4-pregnene-3,11,20-trione) with various bacterial strains (collection of IEP GmbH) are reported.
Biotransformations of cortisone
COSTA, Stefania;PEDRINI, Paola;GIOVANNINI, Pier Paolo
2011
Abstract
Steroid compounds can be ranked among the most widely marketed products from the pharmaceutical industry.1 Highly specific reactions are required to produce functionalized compounds with therapeutic use and commercial value. The complexity of steroid molecules renders the use of biocatalysts particularly interesting, due to the high regio- and stereo-selectivity of the reactions to be performed. In the field the biotrasformations of cortisone (17α,21-dihydroxy-4-pregnene-3,11,20-trione) with various bacterial strains (collection of IEP GmbH) are reported.File in questo prodotto:
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