Medpor® is an alloplastic material largely employed for correcting cranial and facial defects. Implants make with this biomaterial are flexible, stable, and exhibit rapid soft-tissue growth. To better understand the molecular mechanism by which this biomaterial promote bone formation, the expression levels of bone related genes were analyzed in human stem cells isolated from adipose tissue and cultivated on Medpor®. Medpor® enhances proliferation, differentiation and deposition of matrix in stem cells by the activation of osteoblast related genes SP7, COL3A1 and ALPL
MEDPOR® STIMULATES ADIPOSE TISSUE-DERIVED STEM CELLS DIFFERENTIATION
CARINCI, Francesco;PALMIERI, Annalisa;ZOLLINO, Ilaria;SOLLAZZO, Vincenzo
2011
Abstract
Medpor® is an alloplastic material largely employed for correcting cranial and facial defects. Implants make with this biomaterial are flexible, stable, and exhibit rapid soft-tissue growth. To better understand the molecular mechanism by which this biomaterial promote bone formation, the expression levels of bone related genes were analyzed in human stem cells isolated from adipose tissue and cultivated on Medpor®. Medpor® enhances proliferation, differentiation and deposition of matrix in stem cells by the activation of osteoblast related genes SP7, COL3A1 and ALPLFile in questo prodotto:
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