Tumor necrosis factor alpha (TNF-alpha) seems to play a key role in the pathogenesis of Langerhans' cell histiocytosis (LCH). Thalidomide is an immunomodulator agent of inflammatory cytokines including TNF-alpha. To our knowledge this is the first case of disseminated LCH successfully treated with thalidomide.

A case of disseminated Langerhans' cell histiocytosis treated with thalidomide

MAURO, Endri;FRAULINI, Chiara;RIGOLIN, Gian Matteo;GALEOTTI, Roberto;SPANEDDA, Romedio;CASTOLDI, Gianluigi
2005

Abstract

Tumor necrosis factor alpha (TNF-alpha) seems to play a key role in the pathogenesis of Langerhans' cell histiocytosis (LCH). Thalidomide is an immunomodulator agent of inflammatory cytokines including TNF-alpha. To our knowledge this is the first case of disseminated LCH successfully treated with thalidomide.
2005
Mauro, Endri; Fraulini, Chiara; Rigolin, Gian Matteo; Galeotti, Roberto; Spanedda, Romedio; Castoldi, Gianluigi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1208014
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