The role of tachykininis in airway inflammation has been extensively demonstrated in experimental animal models, but evidence in humans is very sparse. The aim of this study was first to quantify the content of substance P (SP) in sputum of a group of patients, with chronic obstructive pulmonary disease and with exposure to occupational irritants. Secondly, to compare them with sputum SP content of a group of control subjects.
Substance P in sputum of patients with chronic obstructive pulmonry disease and occupational exposure to respiratory irritants
BOSCHETTO, Piera;QUINTAVALLE, Sonia;MAZZETTI, Lucia;MIOTTO, Deborah;BONONI, Ilaria;MAPP, Cristina;DE ROSA, Edoardo
2003
Abstract
The role of tachykininis in airway inflammation has been extensively demonstrated in experimental animal models, but evidence in humans is very sparse. The aim of this study was first to quantify the content of substance P (SP) in sputum of a group of patients, with chronic obstructive pulmonary disease and with exposure to occupational irritants. Secondly, to compare them with sputum SP content of a group of control subjects.File in questo prodotto:
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