Histology revealed scattered lymphoid cells at all levels of the digestive tract of the sea bass Dicentrarchus labrax (L.), notably in the mucosa and submucosa. Immunohistochemistry with monoclonal antibodies against T cells (DLT15) and immunoglobulin-bearing cells (DLIg3 and DLIg13) demonstrated the presence of a gut-associated lymphoid tissue. Quantitative analysis showed that the concentration of DLT15-positive cells largely exceeded that of Ig-bearing cells, while the number and the distribution of DLIg3- and DLIg13-immunoreactive cells were superimposable. An apparent gradient in the number of lymphoid cells was present, concentrating them towards the anus. This suggests that, as in other fish species, the posterior gut acquired higher immunological relevance.

Immunohistochemistry of gut-associated lymphoid tissue of the sea bass Dicentrarchus labrax (L.)

ABELLI, Luigi;
1997

Abstract

Histology revealed scattered lymphoid cells at all levels of the digestive tract of the sea bass Dicentrarchus labrax (L.), notably in the mucosa and submucosa. Immunohistochemistry with monoclonal antibodies against T cells (DLT15) and immunoglobulin-bearing cells (DLIg3 and DLIg13) demonstrated the presence of a gut-associated lymphoid tissue. Quantitative analysis showed that the concentration of DLT15-positive cells largely exceeded that of Ig-bearing cells, while the number and the distribution of DLIg3- and DLIg13-immunoreactive cells were superimposable. An apparent gradient in the number of lymphoid cells was present, concentrating them towards the anus. This suggests that, as in other fish species, the posterior gut acquired higher immunological relevance.
1997
Abelli, Luigi; Picchietti, S.; Romano, N.; Mastrolia, L.; Scapigliati, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1196750
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