In this paper we address goals 2 and 3 of those proposed by the donors of the Hepatitis dataset, namely to evaluate whether it is possible to estimate the stage of liver fibrosis from the results of examinations, and to evaluate the effectiveness of the interferon therapy. Goal 2 was addressed by learning various classifiers that predict the value of fibrosis from the values of examinations other than the biopsy. Unfortunately, the best accuracy obtained was only 50.6 %, up only 2.1 % from the performance of the default classifier, thus showing that replacing biopsies is still very hard if not impossible. As regards goal 3, we have plotted the distribution of the values of the difference in fibrosis and in activity before and after the interferon therapy. The plots show that the therapy actually reduces the level of activity but not the level of fibrosis. Moreover, we have also plotted the distribution of the values of the difference of GOT before and after the therapy. The graph shows that a moderate reduction of GOT is obtained.
Classification and visualization on the hepatitis dataset
RIGUZZI, Fabrizio
2004
Abstract
In this paper we address goals 2 and 3 of those proposed by the donors of the Hepatitis dataset, namely to evaluate whether it is possible to estimate the stage of liver fibrosis from the results of examinations, and to evaluate the effectiveness of the interferon therapy. Goal 2 was addressed by learning various classifiers that predict the value of fibrosis from the values of examinations other than the biopsy. Unfortunately, the best accuracy obtained was only 50.6 %, up only 2.1 % from the performance of the default classifier, thus showing that replacing biopsies is still very hard if not impossible. As regards goal 3, we have plotted the distribution of the values of the difference in fibrosis and in activity before and after the interferon therapy. The plots show that the therapy actually reduces the level of activity but not the level of fibrosis. Moreover, we have also plotted the distribution of the values of the difference of GOT before and after the therapy. The graph shows that a moderate reduction of GOT is obtained.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
